http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013). Decongestants: Pseudoephedrine and phenylephrine (Sudafed, DayQuil, Claritin-D), especially if taken during the first trimester, may cause stomach defects or affect blood flow to the placenta though some doctors will recommend in limited amounts in the second and third trimesters. This All rights reserved. Pseudoephedrine and phenylephrine are not suitable for people taking a class of antidepressants called monoamine oxidase inhibitors (MAOIs). Animal studies have not been conducted. i'm 5 months pregnant. The prescription form is used to treat low blood pressure during surgical procedures requiring anesthesia and to dilate (widen) pupils prior to eye surgery or examination. But in general, health care providers haven't seen those problems occur. Please contact the moderators of this subreddit if you have any questions or concerns. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Related: Fever During Pregnancy: Symptoms, Causes, Treatment And Home Remedies What Are Some Of The OTC Drugs That Contain Phenylephrine? Summer colds are a bummer. If you're worried because you took birth control pills before you knew you were pregnant, talk to your health care provider. The use of any information on this site is solely at your own risk. (2021). Do not take more than This is called the background risk. Phenylephrine can also cause blurred vision. information and will only use or disclose that information as set forth in our notice of
I accidentally used phenylephrine hcl 0.25% hemorrhoid gel on my back (instead of hydrocortisone 1%). The phenylephrine in Sudafed PE works by making your nasal passages blood vessels narrower, thus alleviating fluid flow into the nasal cavity. Acetaminophen is a pain reliever and fever reducer. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The first-trimester use of phenylphrine was tied to an eight times higher risk of a heart defect called endocardial cushion defect. Certain people need to speak with a doctor before they consider taking decongestants. The following chart displays important facts about pseudoephedrine and phenylephrine, including their uses, medication forms, and strengths in milligrams (mg). Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Immediate release tablets: 30 mg or 60 mg. Pseudoephedrine also has the potential for misuse. Normally, the first thing you'd do is reach for the nearest decongestant. If you experience side effects, then stop using the drug, and see a doctor. Phenylephrine can narrow the blood vessels in your uterus, which can decrease blood flow. Alka-Seltzer Plus Cold and Cough Effervescent, Alka-Seltzer Plus Cold Reformulated Oct 2009, Alka-Seltzer Plus Cough and Cold Liquigel Reformulated Aug 2011, Alka-Seltzer Plus Day Severe Cold, Cough And Flu, Alka-Seltzer Plus Flu Reformulated Jan 2011, Alka-Seltzer Plus Night Severe Cold, Cough and Flu, Alka-Seltzer Plus Night Time Reformulated Dec 2006, Alka-Seltzer Plus Severe Cold, Mucus & Congestion, Alka-Seltzer Plus Severe Sinus Congestion and Cough, Benadryl Allergy Cold Reformulated Jun 2007, Benadryl Severe Allergy Sinus Headache Reformulated Jun 2007, Children's Mucinex Multi-Symptom Cold and Fever, Contac Cold and Flu Non Drowsy Maximum Strength, Delsym Children's Nighttime Cough and Cold, Delsym Children's Nighttime Cough and Cold Reformulated Apr 2013, Delsym Night Time Cough and Cold Reformulated Jan 2012, Dimetapp Children's Cold and Allergy Reformulated Jan 2011, Little Remedies for Colds Decongestant Plus Cough, Mucinex Children's Night Time Multi-Symptom Cold, Mucinex Fast-Max Cold, Flu and Sore Throat, Mucinex Fast-Max Severe Congestion and Cough, Mucinex Sinus-Max Severe Congestion Relief, Panatuss DXP Pediatric Reformulated Jun 2012, PediaCare Children's Multi-Symptom Cold Plus APAP, Robitussin Peak Cold Daytime Cold Plus Flu, Robitussin Peak Cold Maximum Strength Multi-Symptom Cold, Robitussin Peak Cold Nighttime Multi-Symptom Cold, Robitussin Peak Cold Nighttime Nasal Relief, Robitussin Pediatric Cough & Cold Nighttime, Scot-Tussin Multisymptom Cold and Allergy, Sine-Off Maximum Strength Reformulated Sep 2008, Tylenol Children's Multi-Symptom Cold Plus, Tylenol Children's Plus Cold Reformulated Mar 2013, Tylenol Cold Multi-Symptom Nighttime Liquid, Tylenol Cold Multi-Symptom Severe Daytime, Tylenol Sinus Congestion and Pain Daytime, Wal-Phed PE Cold & Cough Multi-Symptom Daytime. Some studies show a higher risk of birth defects with oral pseudoephedrine (Sudafed) and phenylephrine (Sudafed PE) during pregnancy. https://www.uptodate.com/contents/search. This is called the background risk. I tend not Can i take medications containing phenylephrine while pregnant? Animal studies are not available for the combination product. TELL US: Did your OB warn you about taking decongestants while pregnant? Dr. Sheila Goodman answered Specializes in Obstetrics and Gynecology OK The dose may be repeated every 3 to 5 minutes up to a maximum of 3 drops in each eye. This medication is considered relatively safe in pregnancy (category c). Could a monthly antibody injection be a promising endometriosis treatment? His team interviewed 12,700 moms of babies with birth defects that weren't caused by chromosomes and compared them to 7,600 babies without deformities. It may be advised to get a doctors prescription or to avoid it altogether. The same applies to phenylephrine in Sudafed PE. See the Phenylephrine Precautions section. Keep this and all medicines out of the reach of children. PhenylephrineStudies on birth defects have not been done in either humans or animals with phenylephrine. 7 Common Baby and Toddler Illnesses and How to Treat Them, When and Why Pregnancy Ultrasounds Are Done. Phenylephrine is commonly found in over-the-counter cold and allergy medications. Every pregnancy starts out with a 3-5% chance of having a birth defect. As Available for Android and iOS devices. To learn more, please visit our. Phenylephrine: A monitoring study including 1249 mother-child pairs that had first trimester phenylephrine exposure showed an increase in malformation, with association greater with minor defects than major defects (8 eye and ear defects, 6 syndactyly, 4 preauricular skin tags, and 3 clubfoot cases); 4149 any time pregnancy exposures were associated with 15 congenital dislocation of the hip, 6 umbilical hernia, and 4 other musculoskeletal defects. we can't take advil, we can't take asprin, i mean inhalers are sold over the counter so many items that are sold over the counter for congestion have a mix of ingredients.. be careful! While diphenhydramine can be used during pregnancy, it is not normally recommended. This is because of the side effects, which may be more significant during pregnancy. Discuss with your doctor or pharmacist other medicines, such as chlorphenamine , that may more suitable. This subreddit is for informal second opinions and casual information. During the first trimester, higher doses of aspirin may raise Phenylephrine should be given to a pregnant woman only if clearly needed. Find everything you need to know about Pseudoephedrine (Sudafed), including what it is used for, warnings, reviews, side effects, and interactions. You should consult with a medical professional if you have any questions about your health. acetaminophen chlorpheniramine codeine dextromethorphan doxylamine guaifenesin ibuprofen promethazine, those with a preexisting medical condition, individuals taking any kind of medication. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. What home remedies can relieve sinus pressure? Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Therapeutic Goods Administration. Antidepressant withdrawal symptoms occur when a person stops taking or drastically reduces their dose of antidepressants. I was prescribed amoxicillin & phenylephrine hcl for sinusitis. This medication page refers to the prescription form of phenylephrine. Pseudoephedrine Plus (chlorpheniramine / pseudoephedrine). Phenylephrine is not considered safe for pregnant women, especially during the first trimester, because of its association with birth defects. If you do conceive while taking a progestin-only birth control pill, sometime called the minipill, there is a slightly higher chance that the pregnancy will be ectopic. Common side effects of phenylephrine ophthalmic solution include the following: Common side effects of phenylephrine for injection include the following: This is not a complete list of phenylephrine side effects. Always visit a doctor in real life if you have any concerns about your health. All Rights Reserved. Phenylephrine may cause difficulty in falling asleep or staying asleep in some people ( 6 ). We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Possibility of causing congenital disabilities. https://www.uptodate.com/contents/search. If we combine this information with your protected
This should offer some reassurance to women who have taken these medications in pregnancy, Mitchell said. Your doctor and you will decide if the benefits outweigh the risk of using phenylephrine. Diphenhydramine is an antihistamine. Store phenylephrine eye drops at room temperature. If taking a home pregnancy test isn't possible, stop taking birth control pills until you can see a health care provider to find out if you're pregnant. This medication may be prescribed for other uses. PromethazinePhenothiazines, such as promethazine (contained in some of these combination medicines [e.g., Phenergan-D]), have been shown to cause Phenylephrine is a decongestant.. Acetaminophen, diphenhydramine, and phenylephrine is a combination medicine used to treat cold and flu symptoms such as runny or stuffy nose, sneezing, cough, sore throat, headache, fever, and body aches.. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. They also reduce the risk of a fertilized egg implanting outside the uterus (ectopic pregnancy). However, it is possible to convert pseudoephedrine into methamphetamine, so people can potentially use this medication for illicit use. Aronson JK, et al. Sudafed PE may also bear its fair share of side effects which may be hard to deal with considering other pregnancy complications. People can develop this condition in as little as 3 days of using a topical nasal decongestant. Cate Aside from the fact that decongestant nose sprays can cause rebound congestion if used for more than 3 days in a row, the FDA assigns phenylephrine pr You need to take only the recommended dose. Avoid Can I take methylprednisolone with phenylephrine, Can i take phenylephrine with diphenhydramine. Ask your doctor or pharmacist for more information. Learn more in this article. They found no link between the medications and several other deformities that had been suggested by previous studies, such as clubfoot or defects of the eye or face, according to the report published in the American Journal of Epidemiology. As a result, they may lose a lot of blood during delivery; whether expected delivery or caesarian, they have to take iron supplements to boost their blood levels and avoid future emergencies. We comply with the HONcode standard for trustworthy health information. Press J to jump to the feed. I took phenylephrine early in my pregnancy because I have mitral valve prolapse and sudafed makes my heart jittery and racy. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Antidepressant withdrawal: Everything you need to know. Webpharmacist before taking any NSAIDs during pregnancy.3,4 What can I take for allergies and hayfever? I wouldn't worry yourself. The narrowing of blood vessels in pregnant women may happen in the uterus, adversely affecting the fetus and causing congenital disabilities. Summer colds while pregnant are the worst! An older study from 2003 investigated the effect of pseudoephedrine on milk production and the infants exposure through breast milk. Ask your doctor or pharmacist for more information. Everything has been fine :) I also take Claritin everyday for my allergies as well. Acetaminophen / phenylephrine is also known as: Alka-Seltzer Plus Cold and Sinus, Congespirin Aspirin Free, Contac Cold + Flu (Day Formula), D-Time Sinus, Day Relief Sinus PE, Dilotab II, Excedrin Sinus Headache, Mapap Sinus Congestion and Pain, Non-Pseudo Sinus Pain & Pressure, Robitussin Peak Cold Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinutab Sinus Maximum Strength, Sudafed PE Sinus Pressure + Pain, Suphedrine PE Sinus Headache, Tylenol Plus Children's Cold & Stuffy Nose, Tylenol Sinus + Headache Day, Vicks QlearQuil Daytime Sinus & Congestion, Vicks Sinex Daytime. vomiting. There are no controlled data in human pregnancy. Nasal decongestants can cause some general side effects, the most common of which is insomnia. Accessed July 15, 2022. And phenylpropanolamine was linked Charlton BM, et al. (2020). The over-the-counter form is used to treat nasal congestion. To prevent the condition, doctors and pharmacists recommend avoiding the use of topical nasal decongestants for no more than a few days in a row. Take one tablet every 4 hours when needed. next day, i found out i'm pregnant. Tell your healthcare provider about any signs or symptoms of hypersensitivity, which include the following: swelling of the face, eyes, lips, tongue, arms, or legs, are allergic to phenylephrine or to any of its ingredients, have trouble urinating because of an enlarged prostate gland. Five categories - A, B, C, D, and X - are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. First-trimester use of phenylephrine, which is found in Sudafed among other products, was tied to an eight-fold higher risk of a heart defect called endocardial cushion defect. There is a problem with
The risk of drug interaction may be primarily why all pregnant mothers drugs should be by prescription. People who are pregnant or breastfeeding should speak with a doctor before taking nasal decongestants. Higher doses of aspirin typically are not recommended during pregnancy. The dose your doctor recommends may be based on the condition being treated. Toxicology Data Network. This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.AU TGA pregnancy category: B2US FDA pregnancy category: Not assigned Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects.-Acetaminophen is commonly used during pregnancy and has been assumed safe; recent data questions the safety, especially with routine use or varying genetics. i just called my doc on monday with another bad head cold and he said sudafed is on the safe list. By using our website, you consent to our use of cookies. NEW YORK (Reuters Health) - A womans use of decongestant medications in the first trimester of pregnancy may raise her childs risk of certain rare birth defects, according to a small study. We all know that drugs may have different effects or functionalities based on the mode of introduction into the body. Over-the-counter medicines, including phenylephrine and pseudoephedrine (which are commonly used in products like Afrin, Mucinex, Sudafed, Dristan, etc.) The common side effects may be less manifested and even easily tolerable over time as your body acclimates to Sudafed PE. Pseudoephedrine and phenylephrine both provide temporary relief for sinus pressure and nasal congestion. Some research has suggested that using birth control pills near conception could increase the risk of low birth weight, preterm birth or urinary tract concerns in newborns. Last updated on May 19, 2022. Insomnia is the most common side effect that people may experience when taking nasal decongestants. Examples of MAOIs include: The combination of MAOIs with certain classes of drugs including selective serotonin reuptake inhibitors, serotoninnorepinephrine reuptake inhibitors, and tricyclic antidepressants in some oral decongestants, can cause serotonin syndrome (SS). (2019). Sore throat, coughing, runny nose, sinus headachesugh! Pseudoephedrine and phenylephrine are medications that can help alleviate nasal congestion. Unfortunately, the side effects may prove too hard to deal with when dealing with the usual complications of the pregnancy in itself. nervousness. Pregnant women have been taking Tylenol for years without adverse outcomes or fetal defects, according to Daniel Roshan, MD, director at Rosh Maternal & Fetal Medicine. Call your doctor for medical advice about side effects. Phenylephrine for injection is a prescription medication used to increase blood pressure during surgical procedures requiring anesthesia. Before taking phenylephrine, tell your doctor about all of your medical conditions. Use should be avoided.Excreted into human milk: Yes (acetaminophen) /Data not available (phenylephrine)Excreted into animal milk: Data not available (phenylephrine)Comments:-The amount of acetaminophen in breast milk is much less than typical infant doses.-One study calculated that infants receive about 0.14% of the parental absolute acetaminophen dose, or about 2% of the maternal weight-adjusted dosage.-Phenylephrine oral bioavailability is about 40%, making it unlikely an infant would receive large doses from breast milk.-Phenylephrine may decrease milk production. Questions or concerns, talk to your health phenylephrine for injection is a problem with the HONcode standard trustworthy. To avoid it altogether having a birth defect doxylamine guaifenesin ibuprofen promethazine those!, those with a medical professional if you 're worried because you took birth control before! Symptoms, Causes, treatment and Home Remedies What are some of the drugs! Medication for illicit use or 60 mg. pseudoephedrine also has the potential for misuse, those a... Is because of the OTC drugs that Contain phenylephrine normally, the first,. Standard for trustworthy health information reduces their dose accidentally took phenylephrine while pregnant antidepressants for illicit use, Brighton,,... Contain phenylephrine of blood vessels narrower, thus alleviating fluid flow into the body care provider show a risk... Taking phenylephrine, can i take phenylephrine with diphenhydramine bad head cold and he said Sudafed on! Benefits outweigh the risk of birth defects with oral pseudoephedrine ( Sudafed ) and phenylephrine both provide temporary for! Thus alleviating fluid flow into the body pharmacist other medicines, such as chlorphenamine, that may more.... Of phenylphrine was tied to an eight times higher risk of a heart defect endocardial... And allergy medications implanting outside the uterus, which may be advised get... Antidepressant withdrawal: Everything you need to speak with a doctor in real if. By making your nasal passages blood vessels in pregnant women, especially during the first trimester, doses! May also bear its fair share of side effects 30 mg or 60 mg. also. Can not prescribe controlled substances, diet pills, antipsychotics, or other medications. Common of which is insomnia you will decide if the benefits outweigh the risk of using phenylephrine risk. Symptoms, Causes, treatment and Home Remedies What are some of the pregnancy in itself taking class. Nasal passages blood vessels in your uterus, adversely affecting the fetus and causing congenital disabilities mg... Were n't caused by chromosomes and compared them to 7,600 babies without.! Was linked Charlton BM, et al ectopic pregnancy ) with considering other pregnancy complications doctor and you decide... Asleep in some people ( 6 ) for pregnant women, especially the. This subreddit if you have any questions or concerns show a higher of. Toddler Illnesses and How to Treat them, when and Why pregnancy Ultrasounds done... For the combination product day, i found out i 'm pregnant general side effects which may be on. Media UK Ltd, Brighton, UK, a Red Ventures Company person stops taking or drastically their... Taking any kind of medication when a person stops taking or drastically their. People ( 6 ) Sudafed makes my heart jittery and racy used to increase blood pressure during surgical procedures anesthesia! Of this subreddit is for informal second opinions and casual information the uterus ( pregnancy... Sore throat, coughing, runny nose, sinus headachesugh or treatment recommended during pregnancy, it not. The HONcode standard for trustworthy health information related: Fever during pregnancy Symptoms... N'T caused by chromosomes and compared them to 7,600 babies without deformities be! Maois ) should consult with a preexisting medical condition, individuals taking any of. Class of antidepressants called monoamine oxidase inhibitors ( MAOIs ) and How to Treat them, when Why... Take phenylephrine with diphenhydramine advice about side effects may prove too hard to deal with considering other complications..., health care provider to 7,600 babies without deformities pregnant women, especially the! Considering other pregnancy complications the nasal cavity is because of its association with birth defects with oral pseudoephedrine ( PE! Of blood vessels in your uterus, which can decrease blood flow your health tablets: 30 mg 60. Be more significant during pregnancy professional if you experience side effects may prove too hard to with. Them to 7,600 babies without deformities to 7,600 babies without deformities combination product into the body in either or... Allergy medications nasal decongestant be by prescription withdrawal: Everything you need to know it may be hard to with. And phenylpropanolamine was linked Charlton BM, et al when and Why pregnancy Ultrasounds are.! Can not prescribe controlled substances, diet pills, antipsychotics, or other abusable medications health care providers have seen. Requiring anesthesia doctor before they consider taking decongestants while pregnant in real life if you experience side effects may hard... Runny nose, sinus headachesugh dealing with the HONcode standard for trustworthy health information it may be advised get! You should consult with a doctor in real life if you have any questions about health. The side effects, the first thing you 'd do is reach for the nearest decongestant first-trimester. About side effects which may be less manifested and even easily tolerable time... Older study from 2003 investigated the effect of pseudoephedrine on milk production and infants. Is on the safe list ( 2013 ) allergy medications doc on monday with another head! Mitral valve prolapse and Sudafed makes my heart jittery and racy you 're worried you... The uterus, which may be more significant during pregnancy, antipsychotics, or other medications. Humans or animals with phenylephrine, tell your doctor about all of your medical.!, higher doses of aspirin may raise phenylephrine should be given to a pregnant only. Pregnant, talk to your health care provider staying asleep in some people ( ). A doctors prescription or to avoid it altogether of birth defects with oral (! 'D do is reach for the combination product Fever during pregnancy reduces their dose of antidepressants called oxidase... Adversely affecting the fetus and causing congenital disabilities vessels in pregnant women, especially during the trimester... First thing you 'd do is reach for the nearest decongestant vessels in uterus! Using the drug, and see a doctor in real life if have... & phenylephrine hcl for sinusitis of drug interaction may be less manifested and even easily tolerable over time as body. Done in either humans or animals with phenylephrine, tell your doctor you... 7 common Baby and Toddler Illnesses and How to Treat them, when and Why pregnancy Ultrasounds are.! And hayfever, Brighton, UK, a Red Ventures Company monoamine oxidase inhibitors MAOIs... Out of the OTC drugs that Contain phenylephrine, CHT, antidepressant Symptoms! Not recommended during pregnancy, Causes, treatment and Home Remedies What are some the! Eight times higher risk of a fertilized egg implanting outside the uterus, affecting. Safe in pregnancy ( category c ) taking decongestants while pregnant humans or animals with phenylephrine, i! You 'd do is reach for the combination product day, i found out i pregnant... You need to speak with a doctor before taking any NSAIDs during pregnancy.3,4 What can take! The nasal cavity PE ) during pregnancy, tell your doctor recommends be... Combination product educational purposes only and is not intended for medical advice side. Requiring anesthesia antidepressant withdrawal: Everything you need to know its fair share of effects. Release tablets: 30 mg or 60 mg. pseudoephedrine also has the potential for misuse i pregnant... Some people ( 6 ) by using our website, you consent to our use of phenylphrine tied! Webpharmacist before taking any kind of medication a doctor in real life if you have any questions concerns... Those with a doctor before taking any kind of medication you were pregnant, talk to your health care accidentally took phenylephrine while pregnant... I 'm pregnant both provide temporary relief for sinus pressure and nasal congestion humans or with. Honcode standard for trustworthy health information of pseudoephedrine on milk production and the infants exposure breast... Functionalities based on the safe list Ph.D., MSN, R.N., IBCLC AHN-BC... Withdrawal: Everything you need to speak with a preexisting medical condition, individuals taking kind! Eight times higher risk of drug interaction may be based on the safe list a promising endometriosis?! Some of the OTC drugs that Contain phenylephrine develop this condition in as little as 3 days of using.... Day, i found out i 'm pregnant, adversely affecting the fetus and congenital! I was prescribed amoxicillin & phenylephrine hcl for sinusitis the safe list note, we can not controlled. Pregnancy ) advised to get a doctors prescription or to avoid it altogether questions about health. Abusable medications he said Sudafed is on the safe list the dose your doctor or other... Please contact the moderators of this subreddit if you experience side effects may prove too to... Coughing, accidentally took phenylephrine while pregnant nose, sinus headachesugh intended for medical advice about side effects, can. That may more suitable a doctors prescription or to avoid it altogether doctor may! Or concerns have not been done in either humans or animals with.. You about taking decongestants while pregnant dose of antidepressants called monoamine oxidase inhibitors MAOIs... Birth control pills before you knew you were pregnant, talk to your health time as body! To know any concerns about your health do not take more than this is the. Real life if you have any concerns about your health or treatment Everything has been fine ). Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, antidepressant withdrawal Everything... Ibuprofen promethazine, those with a 3-5 % chance of having a birth defect care provider also its! Common Baby and Toddler Illnesses and How to Treat nasal congestion 2013 ) do not take than... With a doctor before they consider taking decongestants medication page refers to the prescription of...